Radiolucent pedicle screw fixation has become popularized in the field of oncological spine surgery owing to its ability to provide superior post-operative planning for adjuvant radiotherapy and radiological monitoring of tumour progression. We present the case of a 45-year-old female with degenerative spine pathology who underwent L4/5 and L5/S1 posterior lumbar interbody fusion with carbon fibre reinforced-polyetheretherketone pedicle screw fixation. The authors highlight the potential advantages of radiolucent pedicle fixation, which may translate into the degenerative spine surgery domain.