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Adding 3-month patient data improves prognostic models of 12-month disability, pain, and satisfaction after specific lumbar spine surgical procedures: Development and validation of a prediction model. – Back Pain Doctor Harley Street

Adding 3-month patient data improves prognostic models of 12-month disability, pain, and satisfaction after specific lumbar spine surgical procedures: Development and validation of a prediction model.

BACKGROUND CONTEXT:

Prognostic models including early post-operative variables may provide optimal estimates of long-term outcomes and help direct post-operative care.

PURPOSE:

To develop and validate prognostic models for 12-month disability, back pain, leg pain, and satisfaction among patients undergoing microdiscectomy, laminectomy, and laminectomy with fusion for degenerative lumbar conditions.

STUDY DESIGN/SETTING:

Retrospective cohort study using the Quality Outcomes Database.

PATIENT SAMPLE:

Patients receiving elective lumbar spine surgery due to degenerative spine conditions.

OUTCOME MEASURES:

Oswestry Disability Index, pain numerical rating scale, and NASS Patient Satisfaction Index METHODS: Prognostic models were developed using proportional odds ordinal logistic regression using patient characteristics and baseline and 3-month patient reported outcome scores. Models were fit for each outcome stratified by type of surgical procedure. Adjusted odds ratio and 95% confidence intervals were reported for all predictors by procedure. Models were internally validated using bootstrap resampling. Discrimination was reported as the c-index and calibration was presented using the calibration slope. We compared the performance of models with and without 3-month patient-reported variables. This research was supported by the Foundation for Physical Therapy’s Center of Excellence in Physical Therapy Health Services and Health Policy Research and Training Grant.

RESULTS:

The sample consisted of 5840 patients receiving a microdiscectomy (n=2085), laminectomy (n=1837), or laminectomy with fusion (n=1918). The 3-month Oswestry score was the strongest and most consistent predictor associated with 12-month outcomes. All prognostic models performed well with overfitting-corrected c-index values ranging from 0.718 to 0.795 and all optimism corrected calibration slopes over 0.92. The increase in c-index values ranged from 0.09 to 0.21 when adding 3 month patient-reported outcome scores.

CONCLUSIONS:

Models had good discrimination and were well calibrated for estimating 12-month disability, back pain, leg pain, and satisfaction. Patient-reported outcomes at 3-months after surgery, especially 3-month Oswestry scores, improved the 12-month performance of all prognostic models beyond using only baseline variables.

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