Minimally invasive techniques have gained popularity in spine surgery in recent years. Extreme lateral interbody fusion (XLIF) is one of these techniques. The rapid increase in the use of this approach in either primary or revision surgeries is related to its several advantages including less operative time, less blood loss and reduced length of hospital stay with fast recovery. We report a case of a failed transforaminal lumbar interbody fusion (TLIF) in L4-L5 level, one year after the primary procedure with persistent pain due to failed fusion. Underwent revision, by using XLIF with the removal of old cage and exchange with new large cage. Revision of failed interbody fusion can be achieved through anterior, posterior or lateral approach. The decision to proceed with either method depends on several factors, including previous surgeries, fibrosis and risk of neurovascular injury and surgeon’s preference. XLIF approach should be considered in revision surgeries of failed interbody fusion. As it can provide several advantages compared to anterior or posterior approaches, in terms of better fusion rates and lower risk of neurovascular injuries by avoiding the use of the previous passage.