Percutaneous pedicle screw fixation and transforaminal lumbar interbody fusion is a popular minimally invasive technique for fixation and fusion of vertebrae for a variety of indications. It is associated with infrequent but serious well-recognized vascular, visceral and neurological complications. Hereby, we present a case of left main renal artery injury necessitating nephrectomy during lumbar transforaminal interbody fusion of pott’s spine.