Background context:

The advantages of Lateral Single Position surgery (LSPS) in the perioperative period has previously been demonstrated, however 2-year postoperative outcomes of this novel technique have not yet been compared to circumferential anterior-posterior fusion (FLIP) at 2-years postoperatively.

Purpose:

Evaluate the safety and efficacy of LSPS versus gold-standard FLIP STUDY DESIGN/SETTING: Multi-center retrospective cohort review PATIENT SAMPLE: 442 patients undergoing lumbar fusion via LSPS or FLIP OUTCOME MEASURES: Levels fused, operative time, estimated blood loss, perioperative complications, and reasons for reoperation at 30-days, 90-days, 1-year, and 2-years. Radiographic outcomes included lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), PI-LL mismatch, and segmental lumbar lordosis.

Methods:

Patients were grouped as LSPS if anterior and posterior portions of the procedure were performed in the lateral decubitus position, and FLIP if patients were repositioned from supine or lateral to prone position for the posterior portion of the procedure under the same anesthetic. Groups were compared in terms of demographics, intraoperative, perioperative and radiological outcomes, complications and reoperations up to 2 years follow-up. Measures were compared using independent samples or paired t-tests and chi-squared analyses with significance set at p<0.05.

Results:

442 pts met inclusion, including 352 LSPS and 90 FLIP pts. Significant differences were noted in age (62.4 vs. 56.9; p=<0.001) and smoking status (7% vs. 16%; p=0.023) between the LSPS and FLIP groups. LSPS demonstrated significantly lower Op time (97.7min vs 297.0 min; p<0.001), fluoro dose (36.5mGy vs 78.8mGy; p<0.001), EBL (88.8mL vs 270.0mL; p<0.001), and LOS (1.91 days vs. 3.61 days; p<0.001) compared to FLIP. LSPS also demonstrated significantly fewer post-op complications than FLIP (21.9%vs 34.4%; p=0.013), specifically regarding rates of ileus (0.0%vs 5.6%; p<0.001). No differences in reoperation were noted at 30-day (1.7%LSPS vs 4.4%FLIP, p=0.125), 90-day (5.1%LSPS vs 5.6%FLIP, p=0.795) or 2-year follow-up (9.7%LSPS vs 12.2% FLIP; p=0.441). LSPS group had a significantly lower preoperative PI-LL (4.1° LSPS vs 8.6°FLIP, p=0.018), and a significantly greater postoperative LL (56.6° vs 51.8°, p = 0.006). No significant differences were noted in rates of fusion (94.3% LSPS vs 97.8% FLIP; p=0.266) or subsidence (6.9% LSPS vs 12.2% FLIP; p=0.260).

Conclusions:

LSPS and circumferential fusions have similar outcomes at 2-years post-operatively, while reducing perioperative complications, improving perioperative efficiency and safety.