Objective:

To summarize the advances in research on Cage subsidence following lumbar interbody fusion, and provide reference for its prevention.

Methods:

The definition, development, clinical significance, and related risk factors of Cage subsidence following lumbar interbody fusion were throughout reviewed by referring to relevant domestic and doreign literature in recent years.

Results:

At present, there is no consensus on the definition of Cage subsidence, and mostly accepted as the disk height reduction greater than 2 mm. Cage subsidence mainly occurs in the early postoperative stage, which weakens the radiological surgical outcome, and may further damage the effectiveness or even lead to surgical failure. Cage subsidence is closely related to the Cage size and its placement location, intraoperative endplate preparation, morphological matching of disk space to Cage, bone mineral density, body mass index, and so on.

Conclusion:

The appropriate size and shape of the Cage usage, the posterolateral Cage placed, the gentle endplate operation to prevent injury, the active perioperative anti-osteoporosis treatment, and the education of patients to control body weight may help to prevent Cage subsidence and ensure good surgical results.

目的:

总结腰椎椎间融合术后椎间融合器沉降的临床研究进展，以期为该并发症的防治提供参考。.

方法:

广泛查阅近年来国内外相关文献，对腰椎椎间融合术后椎间融合器沉降的定义、发生发展规律、临床意义及危险因素等相关研究进展进行总结。.

结果:

目前，椎间融合器沉降的定义尚未统一，大部分文献将其定义为术后椎间隙高度降低超过 2 mm。椎间融合器沉降主要发生在术后早期。该并发症的发生从影像学上减弱了手术结果，进而影响临床效果，甚至导致手术失败。其发生与椎间融合器的尺寸和位置、术中椎体终板的处理、椎间融合器-椎间隙形态匹配情况、骨密度、体质量指数等多种因素密切相关。.

结论:

术前选择合适尺寸和外形的椎间融合器、术中尽量靠后外侧放置椎间融合器、轻柔操作防止椎体终板损伤、围术期积极抗骨质疏松治疗、教育患者适当控制体质量等，对于预防椎间融合器沉降的发生及保证良好手术效果具有重要临床意义。.