An Analysis of Whether a New Formula Can Predict Proximal Junctional Failure in Adult Spinal Deformity Patients with Global Kyphosis


Study design:

A retrospective observational study.


Objectives:

A new formula containing terms for age and sagittal curvature reported by the International Spine Study Group is ideal LL (iLL) = PI – 0.3TK – 0.5Age + 10. However, there are no reports of whether proximal junctional failure (PJF) can be predicted using this formula. We assessed the utility of this formula in PJF in adult spinal deformity (ASD) patients with global kyphosis using the Roussouly classification.


Methods:

Forty-four ASD patients with global kyphosis (mean age 70.0 years) who underwent multiple levels of lateral lumbar interbody fusion combined with posterior instrumentation were included. Patients were divided into two groups: PJF and non-PJF. Demographic, surgical, and radiological parameters were compared. The iLL was calculated according to the new formula, and spinal parameters were compared preoperatively, immediately after, and at the final follow-up.


Results:

PJF occurred in 11 of 42 (25.0%) patients. Patients with PJF had a large preoperative and postoperative TK, but there was no statistically significant difference in iLL between PJF and non-PJF patients (33.4° vs. 30.2°, P = 0.357). In addition, there was no statistically significant difference in LL and iLL changes (ΔiLL) immediately after surgery (19.0° vs. 23.4°, P = 0.379). Furthermore, there was no correlation between ΔiLL immediately after surgery and at the final follow-up and the proximal junctional angle (PJA) at the final follow-up.


Conclusion:

The results of ΔiLL suggest that overcorrection needs to be addressed but that this new formula, including age adjustment, may not predict PJF.


Keywords:

Roussouly classification; adult spinal deformity (ASD); formula; global alignment and proportion score (GAP score); lateral lumbar interbody fusion (LLIF); proximal junctional angle (PJA); proximal junctional failure (PJF).

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