Comparison of prone transpsoas lateral lumbar interbody fusion and transforaminal lumbar interbody fusion for degenerative lumbar spine disease: A retrospective radiographic propensity score-matched analysis


Introduction:

This is the first study to compare the prone transpsoas (PTP) approach for lateral lumbar interbody fusion (LLIF) and transforaminal lumbar interbody fusion (TLIF) through an analysis of radiographic and clinical outcomes.


Materials and methods:

A retrospective chart review of data for patients who underwent the PTP approach or TLIF for degenerative lumbar spine disease was conducted. Propensity score matching was completed through the utilization of a linear regression model with the classification of surgery (PTP vs. TLIF) being used as the indicator (dependent variable) and the radiographic outcomes as covariates (independent variables). Both cohorts (PTP and TLIF) were propensity score matched according to preoperative radiographic parameters using a 1-to-1 ratio to the nearest neighbor. Eleven patients in the TLIF group were matched to an equal number of patients in the PTP group who had similar propensity scores to perform a thorough analysis of clinical and radiographic outcomes.


Results:

The PTP approach significantly improved the lumbar lordosis angle, pelvic tilt, and the pelvic incidence minus lumbar lordosis value when compared to TLIF (p < 0.05). Clinically, the PTP group improved significantly in terms of the Oswestry Disability Index (p < 0.05). That approach also significantly minimized blood loss and hospital stay (p < 0.05). Furthermore, significantly more cages were placed anteriorly in the PTP group than in the TLIF group (p < 0.05). However, the PTP group had a significantly longer duration of radiation exposure (p < 0.05).


Conclusion:

The PTP approach resulted in greater improvement in postoperative radiographic measurements as well as patient-reported outcomes.


Keywords:

Lateral lumbar interbody fusion; Lumbar lordosis; Prone transpsoas; Sagittal alignment; Transforaminal lumbar interbody fusion (TLIF).

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