Multidisciplinary Approach to Multiple Multiresistant Agent Infection of Instrumented Spine Surgery: A Case Report

January 27, 2022

doi: 10.2106/JBJS.CC.21.00472.

Affiliations

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Francisco Xará-Leite et al.

JBJS Case Connect.

2022.

doi: 10.2106/JBJS.CC.21.00472.

Affiliations

¹ Spinal Unit (UVM), Department of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, Portugal.
² Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal.
³ School of Medicine, University of Minho, Braga, Portugal.
⁴ Department of Infectious Diseases, Centro Hospitalar Universitário do Porto, Porto, Portugal.

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Abstract

Case:

We report the case of a patient with consecutive infections with several multidrug-resistant agents-including carbapenem-resistant strains of Klebsiella pneumoniae among others-from a surgical wound infection after lumbar spine fusion, only successfully treated after the resort to novel antibiotics (ceftazidime-avibactam) in combination therapy.

Conclusions:

Multidrug resistance has become a major challenge in today’s medicine. Care should be taken to avoid their emergence, but when present, a multidisciplinary approach is mandatory to ensure clinically up-to-date treatment choices. Multimodal antibiotic schemes tend to show the most promising results, with which successful infection resolution can still be achieved.

Conflict of interest statement

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B768).

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