doi: 10.1016/j.artmed.2022.102243.
Epub 2022 Jan 8.
Affiliations
Affiliations
- 1 Beijing Institute of Technology, School of Mechanical Engineering, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China.
- 2 Beijing Institute of Technology, School of Mechanical Engineering, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. Electronic address: [email protected].
- 3 Western University, School of Health Science, London, ON N6A 4V2, Canada. Electronic address: [email protected].
- 4 University of Western, Department of Medical Imaging and Medical Biophysics, London, ON N6A 5W9, Canada.
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Hao Gong et al.
Artif Intell Med.
2022 Feb.
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doi: 10.1016/j.artmed.2022.102243.
Epub 2022 Jan 8.
Affiliations
- 1 Beijing Institute of Technology, School of Mechanical Engineering, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China.
- 2 Beijing Institute of Technology, School of Mechanical Engineering, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. Electronic address: [email protected].
- 3 Western University, School of Health Science, London, ON N6A 4V2, Canada. Electronic address: [email protected].
- 4 University of Western, Department of Medical Imaging and Medical Biophysics, London, ON N6A 5W9, Canada.
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Abstract
An axial MRI image of the lumbar spine generally contains multiple spinal structures and their simultaneous segmentation will help analyze the pathogenesis of the spinal disease, generate the spinal medical report, and make a clinical surgery plan for the treatment of the spinal disease. However, it is still a challenging issue that multiple spinal structures are segmented simultaneously and accurately because of the large diversities of the same spinal structure in intensity, resolution, position, shape, and size, the implicit borders between different structures, and the overfitting problem caused by the insufficient training data. In this paper, we propose a novel network framework ResAttenGAN to address these challenges and achieve the simultaneous and accurate segmentation of disc, neural foramina, thecal sac, and posterior arch. ResAttenGAN comprises three modules, i.e. full feature fusion (FFF) module, residual refinement attention (RRA) module, and adversarial learning (AL) module. The FFF module captures multi-scale feature information and fully fuse the features at all hierarchies for generating the discriminative feature representation. The RRA module is made up of a local position attention block and a residual border refinement block to accurately locate the implicit borders and refine their pixel-wise classification. The AL module smooths and strengthens the higher-order spatial consistency to solve the overfitting problem. Experimental results show that the three integrated modules in ResAttenGAN have advantages in tackling the above challenges and ResAttenGAN outperforms the existing segmentation methods under evaluation metrics.
Keywords:
Attention module; Axial MRI image; Feature fusion; GAN; Multiple structures; Simultaneous segmentation.
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