Blog

Surgically Managed Malakoplakia of the Spine: A Case Report


doi: 10.2106/JBJS.CC.21.00328.

Affiliations

Item in Clipboard

Amy L Xu et al.


JBJS Case Connect.


.

Abstract


Case:

A 66-year-old woman with polymyositis and recurrent urinary tract infections presented with lumbar pain and progressive lower extremity neuropathy. Imaging showed lytic destruction of the vertebral bone from L2 to L4 with extension into adjacent musculature. Histological examination demonstrated Michaelis-Gutmann bodies consistent with malakoplakia. The patient underwent revision T12-sacrum posterior fusion, L2-5 laminectomy, and anterior L3-4 corpectomy, followed by L2-4 anterior stabilization and a 6-week course of ceftriaxone. At 3 months postoperatively, she was asymptomatic without recurrence.


Conclusion:

Malakoplakia of bone should be considered in the differential diagnosis of lytic bone lesions and can be effectively treated with surgical debulking with penetrative antibiotics.

Conflict of interest statement

The authors declare no potential conflicts of interest with respect to the authorship and/or publication of this article. None of the authors received financial support for this study. Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B640).

Similar articles

References

    1. Damjanov I, Katz SM. Malakoplakia. Pathol Annu. 1981;16(pt 2):103-26.

    1. Stanton MJ, Maxted W. Malacoplakia: a study of the literature and current concepts of pathogenesis, diagnosis and treatment. J Urol. 1981;125(2):139-46.

    1. Wielenberg AJ, Demos TC, Rangachari B, Turk T. Malacoplakia presenting as a solitary renal mass. AJR Am J Roentgenol. 2004;183(6):1703-5.

    1. Yousef GM, Naghibi B, Hamodat MM. Malakoplakia outside the urinary tract. Arch Pathol Lab Med. 2007;131(2):297-300.

    1. Van den Bout AH, Dreyer L. Malacoplakia of bone: a case report. J Bone Joint Surg Br. 1981;63-B(2):254-6.

Additional articles :

Benchmarking surgical indications for adolescent idiopathic scoliosis across time, region, and patie...
Real-time ultrasound-guided epidural catheter placement in infants: a case series
A Radiographic Analysis of Lumbar Fusion Status and Instrumentation Failure After Complex Adult Spin...
Symptomatic change of Bertolotti's syndrome after long-level lumbar spinal fusion: A case report
Is Dislocation Risk due to Posterior Pelvic Tilt Reduced With Direct Anterior Approach Total Hip Art...
Share on facebook
Facebook
Share on twitter
Twitter
Share on linkedin
LinkedIn
Share on vk
VK
Share on pinterest
Pinterest

Back pain Doctor © All rights reserved

Close Menu